Type

Type

Blood

Blood

Part of

Metabolic syndrome

Part of

Metabolic syndrome

Blood biomarker

Insulin

Insulin

Insulin is a hormone secreted by the pancreas that regulates blood sugar levels by helping cells absorb glucose.

Insulin is a hormone secreted by the pancreas that regulates blood sugar levels by helping cells absorb glucose.

Insulin

Normal range

Normal range

17.9-173 pmol/L

17.9-173 pmol/L

Normal range

17.9-173 pmol/L

17.9-173 pmol/L

Normal range

Insulin

Insulin

Insulin is a hormone secreted by the pancreas that regulates blood sugar levels by helping cells absorb glucose.

Insulin

Normal range

17.9-173 pmol/L

Normal range

17.9-173 pmol/L

17.9-173 pmol/L

Normal range

Insulin

Insulin

Insulin is a hormone secreted by the pancreas that regulates blood sugar levels by helping cells absorb glucose.

Insulin

Normal range

17.9-173 pmol/L

Normal range

17.9-173 pmol/L

17.9-173 pmol/L

Normal range

Insulin

Dr. Yiannis Balanos

MBBS MRCGP

Your Body's Blood Sugar Management Hormone

Your Body's Blood Sugar Management Hormone

Every time you eat, your pancreas springs into action, producing insulin to help your cells absorb glucose from your bloodstream and use it for energy. This hormone works as your body's glucose transport coordinator, ensuring that sugar gets delivered efficiently to the cells that need it whilst maintaining stable blood sugar levels.

When insulin production and cellular response work in harmony, your glucose management runs like a well-oiled machine. But when this system becomes disrupted, it can lead to diabetes, metabolic syndrome, or other blood sugar disorders that affect how your body handles energy.

Think of insulin as your body's cellular access key—without it, glucose can't enter your cells where it's needed for energy, leading to a buildup in your bloodstream instead. Understanding your insulin levels provides valuable insights into how well your pancreas is keeping up with your body's demands and whether your cells are still listening to insulin's signals.

Every time you eat, your pancreas springs into action, producing insulin to help your cells absorb glucose from your bloodstream and use it for energy. This hormone works as your body's glucose transport coordinator, ensuring that sugar gets delivered efficiently to the cells that need it whilst maintaining stable blood sugar levels.

When insulin production and cellular response work in harmony, your glucose management runs like a well-oiled machine. But when this system becomes disrupted, it can lead to diabetes, metabolic syndrome, or other blood sugar disorders that affect how your body handles energy.

Think of insulin as your body's cellular access key—without it, glucose can't enter your cells where it's needed for energy, leading to a buildup in your bloodstream instead. Understanding your insulin levels provides valuable insights into how well your pancreas is keeping up with your body's demands and whether your cells are still listening to insulin's signals.

When Your Insulin Production Fails

When Your Insulin Production Fails

When Your Insulin Production Fails

Discover how low insulin levels reveal pancreatic damage and what symptoms signal urgent attention.

Read more

When Your Insulin System Overworks

When Your Insulin System Overworks

When Your Insulin System Overworks

Learn why high insulin levels indicate cellular resistance and metabolic strain.

Read more

What Influences Your Insulin Levels

What Influences Your Insulin Levels

What Influences Your Insulin Levels

Learn about the lifestyle factors, conditions, and genetic variations that affect your body's insulin production and effectiveness.

Read more

Understanding Your Results

Understanding Your Results

Understanding Your Results

Decode your insulin numbers and know what they mean for your metabolic health and diabetes risk.

Read more

When Your Insulin Production Fails

Low insulin levels often indicate that your pancreas has reduced capacity to produce this essential hormone, commonly occurring in type 1 diabetes where your immune system mistakenly attacks the insulin-producing beta cells. This autoimmune process typically affects children and young adults, though it can occur at any age, gradually destroying your body's natural insulin production capacity and creating dependency on insulin replacement therapy.

You might experience increased thirst, frequent urination, unexplained weight loss, and persistent fatigue as your body struggles to manage blood sugar without adequate insulin. These symptoms can develop rapidly in type 1 diabetes and require immediate medical attention, as the condition can become life-threatening without prompt treatment.

When Your Insulin Production Fails

Low insulin levels often indicate that your pancreas has reduced capacity to produce this essential hormone, commonly occurring in type 1 diabetes where your immune system mistakenly attacks the insulin-producing beta cells. This autoimmune process typically affects children and young adults, though it can occur at any age, gradually destroying your body's natural insulin production capacity and creating dependency on insulin replacement therapy.

You might experience increased thirst, frequent urination, unexplained weight loss, and persistent fatigue as your body struggles to manage blood sugar without adequate insulin. These symptoms can develop rapidly in type 1 diabetes and require immediate medical attention, as the condition can become life-threatening without prompt treatment.

When Your Insulin Production Fails

Low insulin levels often indicate that your pancreas has reduced capacity to produce this essential hormone, commonly occurring in type 1 diabetes where your immune system mistakenly attacks the insulin-producing beta cells. This autoimmune process typically affects children and young adults, though it can occur at any age, gradually destroying your body's natural insulin production capacity and creating dependency on insulin replacement therapy.

You might experience increased thirst, frequent urination, unexplained weight loss, and persistent fatigue as your body struggles to manage blood sugar without adequate insulin. These symptoms can develop rapidly in type 1 diabetes and require immediate medical attention, as the condition can become life-threatening without prompt treatment.

When Your Insulin System Overworks

High insulin levels tell a different story, revealing that your pancreas is working overtime to maintain blood sugar control. This typically indicates insulin resistance, where your cells have become less responsive to insulin's signals, forcing your pancreas to produce increasing amounts to achieve the same glucose management results.

This increased insulin production creates a problematic cycle where elevated hormone levels contribute to fat storage and inflammation, which can further reduce insulin sensitivity over time. Eventually, your pancreas may struggle to maintain this increased output, and insulin levels may begin to decline as pancreatic function becomes compromised, marking potential progression toward type 2 diabetes. Understanding these patterns helps identify metabolic changes early, when lifestyle interventions and medical treatments are most effective at preserving pancreatic function and preventing diabetes complications.

When Your Insulin System Overworks

High insulin levels tell a different story, revealing that your pancreas is working overtime to maintain blood sugar control. This typically indicates insulin resistance, where your cells have become less responsive to insulin's signals, forcing your pancreas to produce increasing amounts to achieve the same glucose management results.

This increased insulin production creates a problematic cycle where elevated hormone levels contribute to fat storage and inflammation, which can further reduce insulin sensitivity over time. Eventually, your pancreas may struggle to maintain this increased output, and insulin levels may begin to decline as pancreatic function becomes compromised, marking potential progression toward type 2 diabetes. Understanding these patterns helps identify metabolic changes early, when lifestyle interventions and medical treatments are most effective at preserving pancreatic function and preventing diabetes complications.

When Your Insulin System Overworks

High insulin levels tell a different story, revealing that your pancreas is working overtime to maintain blood sugar control. This typically indicates insulin resistance, where your cells have become less responsive to insulin's signals, forcing your pancreas to produce increasing amounts to achieve the same glucose management results.

This increased insulin production creates a problematic cycle where elevated hormone levels contribute to fat storage and inflammation, which can further reduce insulin sensitivity over time. Eventually, your pancreas may struggle to maintain this increased output, and insulin levels may begin to decline as pancreatic function becomes compromised, marking potential progression toward type 2 diabetes. Understanding these patterns helps identify metabolic changes early, when lifestyle interventions and medical treatments are most effective at preserving pancreatic function and preventing diabetes complications.

What Influences Your Insulin Levels

Factors that impair insulin production include autoimmune processes that destroy pancreatic beta cells in type 1 diabetes, genetic variations affecting insulin production, certain medications, pancreatic diseases or injuries, and chronic pancreatitis.

Factors that increase insulin resistance include excess body weight particularly around the waist, sedentary lifestyles, diets high in refined carbohydrates and processed foods, chronic stress, poor sleep quality, and certain medications like steroids. Consistently consuming high-carbohydrate meals, maintaining excess body weight, or experiencing chronic stress can increase the demands on your pancreas, potentially affecting its long-term insulin-producing capacity.

Your daily choices either support or challenge your pancreatic function. Regular exercise enhances insulin sensitivity and reduces the workload on your pancreas, whilst processed foods, excess weight, and chronic stress can increase insulin demands. Over time, these factors can influence your body's ability to maintain optimal glucose control.

You may be at higher risk for insulin problems if you have a family history of diabetes, are overweight, lead a sedentary lifestyle, have polycystic ovary syndrome, or belong to certain ethnic groups including South Asian, African Caribbean, and Middle Eastern populations who have higher genetic predisposition to diabetes.

What Influences Your Insulin Levels

Factors that impair insulin production include autoimmune processes that destroy pancreatic beta cells in type 1 diabetes, genetic variations affecting insulin production, certain medications, pancreatic diseases or injuries, and chronic pancreatitis.

Factors that increase insulin resistance include excess body weight particularly around the waist, sedentary lifestyles, diets high in refined carbohydrates and processed foods, chronic stress, poor sleep quality, and certain medications like steroids. Consistently consuming high-carbohydrate meals, maintaining excess body weight, or experiencing chronic stress can increase the demands on your pancreas, potentially affecting its long-term insulin-producing capacity.

Your daily choices either support or challenge your pancreatic function. Regular exercise enhances insulin sensitivity and reduces the workload on your pancreas, whilst processed foods, excess weight, and chronic stress can increase insulin demands. Over time, these factors can influence your body's ability to maintain optimal glucose control.

You may be at higher risk for insulin problems if you have a family history of diabetes, are overweight, lead a sedentary lifestyle, have polycystic ovary syndrome, or belong to certain ethnic groups including South Asian, African Caribbean, and Middle Eastern populations who have higher genetic predisposition to diabetes.

What Influences Your Insulin Levels

Factors that impair insulin production include autoimmune processes that destroy pancreatic beta cells in type 1 diabetes, genetic variations affecting insulin production, certain medications, pancreatic diseases or injuries, and chronic pancreatitis.

Factors that increase insulin resistance include excess body weight particularly around the waist, sedentary lifestyles, diets high in refined carbohydrates and processed foods, chronic stress, poor sleep quality, and certain medications like steroids. Consistently consuming high-carbohydrate meals, maintaining excess body weight, or experiencing chronic stress can increase the demands on your pancreas, potentially affecting its long-term insulin-producing capacity.

Your daily choices either support or challenge your pancreatic function. Regular exercise enhances insulin sensitivity and reduces the workload on your pancreas, whilst processed foods, excess weight, and chronic stress can increase insulin demands. Over time, these factors can influence your body's ability to maintain optimal glucose control.

You may be at higher risk for insulin problems if you have a family history of diabetes, are overweight, lead a sedentary lifestyle, have polycystic ovary syndrome, or belong to certain ethnic groups including South Asian, African Caribbean, and Middle Eastern populations who have higher genetic predisposition to diabetes.

Understanding Your Results

Insulin measurements help assess whether your pancreas is producing appropriate amounts of this essential hormone. Healthy individuals with excellent insulin sensitivity may have slightly low insulin levels when fasting. Understanding these ranges provides insight into your metabolic health:

Fasting insulin ranges:


  • Optimal levels: 14-42 pmol/L

  • Normal levels: 18-173 pmol/L

  • Elevated levels: >174 pmol/L (suggests possible insulin resistance)

  • Low levels: <18 pmol/L (may indicate insulin deficiency)


It's important to interpret insulin levels in relation to your glucose level at the time of testing. Your clinician may calculate a score called HOMA-IR, which measures how efficiently your insulin is working for your measured glucose level, providing additional insight into your metabolic function.

Taking Action Based on Your Results

Elevated insulin levels often respond well to lifestyle modifications aimed at improving insulin sensitivity. Weight management, regular exercise, stress reduction, and dietary changes can significantly improve how your cells respond to insulin and reduce the workload on your pancreas.

Low insulin levels typically require medical evaluation to determine appropriate treatment options, which may include insulin replacement therapy or other interventions to support glucose management and prevent complications.

Understanding Your Results

Insulin measurements help assess whether your pancreas is producing appropriate amounts of this essential hormone. Healthy individuals with excellent insulin sensitivity may have slightly low insulin levels when fasting. Understanding these ranges provides insight into your metabolic health:

Fasting insulin ranges:


  • Optimal levels: 14-42 pmol/L

  • Normal levels: 18-173 pmol/L

  • Elevated levels: >174 pmol/L (suggests possible insulin resistance)

  • Low levels: <18 pmol/L (may indicate insulin deficiency)


It's important to interpret insulin levels in relation to your glucose level at the time of testing. Your clinician may calculate a score called HOMA-IR, which measures how efficiently your insulin is working for your measured glucose level, providing additional insight into your metabolic function.

Taking Action Based on Your Results

Elevated insulin levels often respond well to lifestyle modifications aimed at improving insulin sensitivity. Weight management, regular exercise, stress reduction, and dietary changes can significantly improve how your cells respond to insulin and reduce the workload on your pancreas.

Low insulin levels typically require medical evaluation to determine appropriate treatment options, which may include insulin replacement therapy or other interventions to support glucose management and prevent complications.

Understanding Your Results

Insulin measurements help assess whether your pancreas is producing appropriate amounts of this essential hormone. Healthy individuals with excellent insulin sensitivity may have slightly low insulin levels when fasting. Understanding these ranges provides insight into your metabolic health:

Fasting insulin ranges:


  • Optimal levels: 14-42 pmol/L

  • Normal levels: 18-173 pmol/L

  • Elevated levels: >174 pmol/L (suggests possible insulin resistance)

  • Low levels: <18 pmol/L (may indicate insulin deficiency)


It's important to interpret insulin levels in relation to your glucose level at the time of testing. Your clinician may calculate a score called HOMA-IR, which measures how efficiently your insulin is working for your measured glucose level, providing additional insight into your metabolic function.

Taking Action Based on Your Results

Elevated insulin levels often respond well to lifestyle modifications aimed at improving insulin sensitivity. Weight management, regular exercise, stress reduction, and dietary changes can significantly improve how your cells respond to insulin and reduce the workload on your pancreas.

Low insulin levels typically require medical evaluation to determine appropriate treatment options, which may include insulin replacement therapy or other interventions to support glucose management and prevent complications.

The Takeaway

Your insulin levels provide valuable information about your pancreatic function and metabolic health, often revealing changes before blood sugar levels become obviously abnormal. Elevated insulin suggests your glucose management system is working harder than optimal, whilst low insulin indicates reduced pancreatic capacity that may need support.

Your insulin levels need to be interpreted in the context of your overall health, and your clinician will be able to support you with this interpretation and provide meaningful insights about your metabolic status and any needed interventions.

Taking appropriate action based on your insulin results can help prevent diabetes progression, preserve your pancreatic function, and support optimal metabolic health. A simple blood test can reveal these crucial insights.

The Takeaway

Your insulin levels provide valuable information about your pancreatic function and metabolic health, often revealing changes before blood sugar levels become obviously abnormal. Elevated insulin suggests your glucose management system is working harder than optimal, whilst low insulin indicates reduced pancreatic capacity that may need support.

Your insulin levels need to be interpreted in the context of your overall health, and your clinician will be able to support you with this interpretation and provide meaningful insights about your metabolic status and any needed interventions.

Taking appropriate action based on your insulin results can help prevent diabetes progression, preserve your pancreatic function, and support optimal metabolic health. A simple blood test can reveal these crucial insights.

The Takeaway

Your insulin levels provide valuable information about your pancreatic function and metabolic health, often revealing changes before blood sugar levels become obviously abnormal. Elevated insulin suggests your glucose management system is working harder than optimal, whilst low insulin indicates reduced pancreatic capacity that may need support.

Your insulin levels need to be interpreted in the context of your overall health, and your clinician will be able to support you with this interpretation and provide meaningful insights about your metabolic status and any needed interventions.

Taking appropriate action based on your insulin results can help prevent diabetes progression, preserve your pancreatic function, and support optimal metabolic health. A simple blood test can reveal these crucial insights.

References

  1. National Institute for Health and Care Excellence. (2021). Type 2 diabetes: prevention and management. NICE Clinical Guideline.

  2. British Diabetic Association. (2020). Insulin testing and diabetes assessment. BDA Practice Standards.

  3. Royal College of Physicians. (2021). Beta cell function and insulin resistance evaluation. RCP Clinical Guidelines.

References

  1. National Institute for Health and Care Excellence. (2021). Type 2 diabetes: prevention and management. NICE Clinical Guideline.

  2. British Diabetic Association. (2020). Insulin testing and diabetes assessment. BDA Practice Standards.

  3. Royal College of Physicians. (2021). Beta cell function and insulin resistance evaluation. RCP Clinical Guidelines.

References

  1. National Institute for Health and Care Excellence. (2021). Type 2 diabetes: prevention and management. NICE Clinical Guideline.

  2. British Diabetic Association. (2020). Insulin testing and diabetes assessment. BDA Practice Standards.

  3. Royal College of Physicians. (2021). Beta cell function and insulin resistance evaluation. RCP Clinical Guidelines.

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