Type

Type

Blood

Blood

Part of

Digestive health

Part of

Digestive health

Blood biomarker

H. Pylori (IgG)

H. Pylori (IgG)

Helicobacter pylori (H. pylori) is a type of bacteria linked to stomach ulcers and gastritis.

Helicobacter pylori (H. pylori) is a type of bacteria linked to stomach ulcers and gastritis.

H. Pylori (IgG)

Normal range

Normal range

Negative: < 81 IU/L

Negative: < 81 IU/L

Normal range

Negative: < 81 IU/L

Negative: < 81 IU/L

Normal range

H. Pylori (IgG)

H. Pylori (IgG)

Helicobacter pylori (H. pylori) is a type of bacteria linked to stomach ulcers and gastritis.

H. Pylori (IgG)

Normal range

Negative: < 81 IU/L

Normal range

Negative: < 81 IU/L

Negative: < 81 IU/L

Normal range

H. Pylori (IgG)

H. Pylori (IgG)

Helicobacter pylori (H. pylori) is a type of bacteria linked to stomach ulcers and gastritis.

H. Pylori (IgG)

Normal range

Negative: < 81 IU/L

Normal range

Negative: < 81 IU/L

Negative: < 81 IU/L

Normal range

H. Pylori (IgG)

Dr. Shad Asinger

MBBS GPST

Your Stomach Infection History

Your Stomach Infection History

Helicobacter pylori is a common bacterium that lives in the stomach lining of approximately half the world's population, often without causing any noticeable symptoms. This spiral-shaped organism has adapted to survive in your stomach's acidic environment, where it can remain for years or even decades. Many people carry H. pylori without realising it, whilst others develop digestive problems including ulcers and gastritis that require medical treatment.

When your immune system encounters H. pylori, it creates specific IgG antibodies that remain in your bloodstream as markers of this bacterial exposure. These antibodies provide doctors with valuable information about whether you've been infected with H. pylori, helping explain persistent digestive symptoms and guiding decisions about testing and treatment for this common stomach infection.

Helicobacter pylori is a common bacterium that lives in the stomach lining of approximately half the world's population, often without causing any noticeable symptoms. This spiral-shaped organism has adapted to survive in your stomach's acidic environment, where it can remain for years or even decades. Many people carry H. pylori without realising it, whilst others develop digestive problems including ulcers and gastritis that require medical treatment.

When your immune system encounters H. pylori, it creates specific IgG antibodies that remain in your bloodstream as markers of this bacterial exposure. These antibodies provide doctors with valuable information about whether you've been infected with H. pylori, helping explain persistent digestive symptoms and guiding decisions about testing and treatment for this common stomach infection.

When H. Pylori Antibodies Indicate Exposure

When H. Pylori Antibodies Indicate Exposure

When H. Pylori Antibodies Indicate Exposure

Discover how positive antibody tests reveal bacterial infection that may be contributing to your digestive symptoms and stomach problems.

Read more

What H. Pylori Does in Your Stomach

What H. Pylori Does in Your Stomach

What H. Pylori Does in Your Stomach

Learn how this persistent bacterium affects your stomach lining and digestive health, sometimes causing ulcers and inflammation.

Read more

The Antibody Response to H. Pylori

The Antibody Response to H. Pylori

The Antibody Response to H. Pylori

Understanding how your immune system responds to this bacterial infection and creates lasting antibody markers.

Read more

Understanding Your Results

Understanding Your Results

Understanding Your Results

Decode your antibody levels and understand what positive or negative results mean for your stomach health and treatment options.

Read more

When H. Pylori Antibodies Indicate Exposure

Positive H. pylori IgG antibodies indicate that your immune system has encountered this bacterium at some point, though they cannot distinguish between current active infection and past exposure that may have been treated. Many people with H. pylori experience no symptoms at all, whilst others develop stomach pain, burning sensations, nausea, or bloating as the bacteria affect their stomach lining.

H. pylori infection often develops gradually, with symptoms that can be mild and intermittent for years before becoming more noticeable. The bacteria can survive in your stomach's acidic environment by producing substances that neutralise acid in their immediate vicinity, allowing them to establish long-term residence in your digestive system.

When symptoms do occur, they typically include recurring stomach discomfort, particularly between meals or during the night, along with bloating, early fullness during meals, or occasional nausea. These symptoms can be easily mistaken for other digestive issues, making antibody testing valuable for identifying H. pylori as a potential cause.

The infection is particularly common in certain populations and geographic regions, with higher rates in developing countries and areas with crowded living conditions. Most infections occur during childhood, often spreading within families, though many people remain unaware they carry the bacteria until testing is performed for other reasons.

When H. Pylori Antibodies Indicate Exposure

Positive H. pylori IgG antibodies indicate that your immune system has encountered this bacterium at some point, though they cannot distinguish between current active infection and past exposure that may have been treated. Many people with H. pylori experience no symptoms at all, whilst others develop stomach pain, burning sensations, nausea, or bloating as the bacteria affect their stomach lining.

H. pylori infection often develops gradually, with symptoms that can be mild and intermittent for years before becoming more noticeable. The bacteria can survive in your stomach's acidic environment by producing substances that neutralise acid in their immediate vicinity, allowing them to establish long-term residence in your digestive system.

When symptoms do occur, they typically include recurring stomach discomfort, particularly between meals or during the night, along with bloating, early fullness during meals, or occasional nausea. These symptoms can be easily mistaken for other digestive issues, making antibody testing valuable for identifying H. pylori as a potential cause.

The infection is particularly common in certain populations and geographic regions, with higher rates in developing countries and areas with crowded living conditions. Most infections occur during childhood, often spreading within families, though many people remain unaware they carry the bacteria until testing is performed for other reasons.

When H. Pylori Antibodies Indicate Exposure

Positive H. pylori IgG antibodies indicate that your immune system has encountered this bacterium at some point, though they cannot distinguish between current active infection and past exposure that may have been treated. Many people with H. pylori experience no symptoms at all, whilst others develop stomach pain, burning sensations, nausea, or bloating as the bacteria affect their stomach lining.

H. pylori infection often develops gradually, with symptoms that can be mild and intermittent for years before becoming more noticeable. The bacteria can survive in your stomach's acidic environment by producing substances that neutralise acid in their immediate vicinity, allowing them to establish long-term residence in your digestive system.

When symptoms do occur, they typically include recurring stomach discomfort, particularly between meals or during the night, along with bloating, early fullness during meals, or occasional nausea. These symptoms can be easily mistaken for other digestive issues, making antibody testing valuable for identifying H. pylori as a potential cause.

The infection is particularly common in certain populations and geographic regions, with higher rates in developing countries and areas with crowded living conditions. Most infections occur during childhood, often spreading within families, though many people remain unaware they carry the bacteria until testing is performed for other reasons.

What H. Pylori Does in Your Stomach

H. pylori bacteria specifically target your stomach lining, where they can cause inflammation and weaken your stomach's natural protective mechanisms. This process happens gradually over time and may not cause immediate symptoms, but can eventually lead to more serious problems including peptic ulcers and chronic gastritis.

The bacteria has a defence mechanism that helps survival in your stomach's acidic environment whilst also releasing toxins that can damage stomach tissue. This ongoing irritation triggers inflammatory responses that can persist for years, potentially affecting your stomach's ability to protect itself from its own acid production.

In some people, H. pylori infection leads to peptic ulcers—painful sores that develop in the stomach or duodenum when the protective lining becomes damaged. These ulcers can cause persistent pain, bleeding, or other complications that require medical treatment to heal properly and prevent recurrence.

Long-term H. pylori infection can also increase the risk of developing stomach cancer, though this typically occurs over many years and affects only a small percentage of infected people. The chronic inflammation caused by persistent bacterial presence can lead to changes that may progress to more serious conditions over time.

What H. Pylori Does in Your Stomach

H. pylori bacteria specifically target your stomach lining, where they can cause inflammation and weaken your stomach's natural protective mechanisms. This process happens gradually over time and may not cause immediate symptoms, but can eventually lead to more serious problems including peptic ulcers and chronic gastritis.

The bacteria has a defence mechanism that helps survival in your stomach's acidic environment whilst also releasing toxins that can damage stomach tissue. This ongoing irritation triggers inflammatory responses that can persist for years, potentially affecting your stomach's ability to protect itself from its own acid production.

In some people, H. pylori infection leads to peptic ulcers—painful sores that develop in the stomach or duodenum when the protective lining becomes damaged. These ulcers can cause persistent pain, bleeding, or other complications that require medical treatment to heal properly and prevent recurrence.

Long-term H. pylori infection can also increase the risk of developing stomach cancer, though this typically occurs over many years and affects only a small percentage of infected people. The chronic inflammation caused by persistent bacterial presence can lead to changes that may progress to more serious conditions over time.

What H. Pylori Does in Your Stomach

H. pylori bacteria specifically target your stomach lining, where they can cause inflammation and weaken your stomach's natural protective mechanisms. This process happens gradually over time and may not cause immediate symptoms, but can eventually lead to more serious problems including peptic ulcers and chronic gastritis.

The bacteria has a defence mechanism that helps survival in your stomach's acidic environment whilst also releasing toxins that can damage stomach tissue. This ongoing irritation triggers inflammatory responses that can persist for years, potentially affecting your stomach's ability to protect itself from its own acid production.

In some people, H. pylori infection leads to peptic ulcers—painful sores that develop in the stomach or duodenum when the protective lining becomes damaged. These ulcers can cause persistent pain, bleeding, or other complications that require medical treatment to heal properly and prevent recurrence.

Long-term H. pylori infection can also increase the risk of developing stomach cancer, though this typically occurs over many years and affects only a small percentage of infected people. The chronic inflammation caused by persistent bacterial presence can lead to changes that may progress to more serious conditions over time.

The Antibody Response to H. Pylori

Your immune system responds to H. pylori infection by producing specific antibodies designed to target the bacteria. Think of antibodies as target seeking missiles created by your body. IgG antibodies represent your body's long-term immune memory, developing weeks to months after initial infection and persisting in your bloodstream for extended periods.

These antibodies can be detected through simple blood tests, making them useful markers for determining whether you've been exposed to H. pylori. The antibodies typically remain detectable long after bacterial exposure occurs, which is why positive results require additional evaluation to determine whether active infection is present.

The strength of your antibody response can vary based on factors including your age, overall immune function, and how long you've been infected. Some people develop strong antibody responses whilst others produce lower levels, though both patterns can indicate significant bacterial exposure.

The Antibody Response to H. Pylori

Your immune system responds to H. pylori infection by producing specific antibodies designed to target the bacteria. Think of antibodies as target seeking missiles created by your body. IgG antibodies represent your body's long-term immune memory, developing weeks to months after initial infection and persisting in your bloodstream for extended periods.

These antibodies can be detected through simple blood tests, making them useful markers for determining whether you've been exposed to H. pylori. The antibodies typically remain detectable long after bacterial exposure occurs, which is why positive results require additional evaluation to determine whether active infection is present.

The strength of your antibody response can vary based on factors including your age, overall immune function, and how long you've been infected. Some people develop strong antibody responses whilst others produce lower levels, though both patterns can indicate significant bacterial exposure.

The Antibody Response to H. Pylori

Your immune system responds to H. pylori infection by producing specific antibodies designed to target the bacteria. Think of antibodies as target seeking missiles created by your body. IgG antibodies represent your body's long-term immune memory, developing weeks to months after initial infection and persisting in your bloodstream for extended periods.

These antibodies can be detected through simple blood tests, making them useful markers for determining whether you've been exposed to H. pylori. The antibodies typically remain detectable long after bacterial exposure occurs, which is why positive results require additional evaluation to determine whether active infection is present.

The strength of your antibody response can vary based on factors including your age, overall immune function, and how long you've been infected. Some people develop strong antibody responses whilst others produce lower levels, though both patterns can indicate significant bacterial exposure.

Understanding Your Results 

H. pylori IgG antibody tests are typically reported as positive or negative, with some laboratories providing numerical values that indicate antibody concentration. Understanding these results helps assess your likelihood of having been exposed to this bacterial infection:


H. pylori IgG results: 

  • Negative: <81.07 IU/L - No detectable antibodies (no evidence of exposure) 

  • Positive: >81.07 IU/L - Antibodies detected (indicates current or past infection)  


A negative result generally indicates that you haven't been infected with H. pylori, though very recent infections might not yet have triggered detectable antibody production. Most people develop antibodies within 6-8 weeks of initial infection.

Understanding Positive Results

Positive H. pylori IgG results indicate exposure to the bacteria but require additional evaluation to determine whether active infection is present. Your doctor may recommend complementary tests such as stool antigen testing or urea breath tests to confirm current bacterial activity before prescribing treatment.

Many people with positive antibody tests have no current symptoms, as H. pylori can remain present without causing obvious problems (i.e. no active infection).

Clinical Decision Making

Your healthcare provider will interpret H. pylori antibody results alongside your symptoms, medical history, and other factors to determine the most appropriate next steps. This might include additional testing to confirm active infection, treatment if clinical evidence suggests current infection, or monitoring if symptoms are minimal.

The decision to treat H. pylori depends on various factors including symptom severity, ulcer history, family history of stomach cancer, and individual risk factors that make treatment more beneficial than continued observation.

Understanding Your Results 

H. pylori IgG antibody tests are typically reported as positive or negative, with some laboratories providing numerical values that indicate antibody concentration. Understanding these results helps assess your likelihood of having been exposed to this bacterial infection:


H. pylori IgG results: 

  • Negative: <81.07 IU/L - No detectable antibodies (no evidence of exposure) 

  • Positive: >81.07 IU/L - Antibodies detected (indicates current or past infection)  


A negative result generally indicates that you haven't been infected with H. pylori, though very recent infections might not yet have triggered detectable antibody production. Most people develop antibodies within 6-8 weeks of initial infection.

Understanding Positive Results

Positive H. pylori IgG results indicate exposure to the bacteria but require additional evaluation to determine whether active infection is present. Your doctor may recommend complementary tests such as stool antigen testing or urea breath tests to confirm current bacterial activity before prescribing treatment.

Many people with positive antibody tests have no current symptoms, as H. pylori can remain present without causing obvious problems (i.e. no active infection).

Clinical Decision Making

Your healthcare provider will interpret H. pylori antibody results alongside your symptoms, medical history, and other factors to determine the most appropriate next steps. This might include additional testing to confirm active infection, treatment if clinical evidence suggests current infection, or monitoring if symptoms are minimal.

The decision to treat H. pylori depends on various factors including symptom severity, ulcer history, family history of stomach cancer, and individual risk factors that make treatment more beneficial than continued observation.

Understanding Your Results 

H. pylori IgG antibody tests are typically reported as positive or negative, with some laboratories providing numerical values that indicate antibody concentration. Understanding these results helps assess your likelihood of having been exposed to this bacterial infection:


H. pylori IgG results: 

  • Negative: <81.07 IU/L - No detectable antibodies (no evidence of exposure) 

  • Positive: >81.07 IU/L - Antibodies detected (indicates current or past infection)  


A negative result generally indicates that you haven't been infected with H. pylori, though very recent infections might not yet have triggered detectable antibody production. Most people develop antibodies within 6-8 weeks of initial infection.

Understanding Positive Results

Positive H. pylori IgG results indicate exposure to the bacteria but require additional evaluation to determine whether active infection is present. Your doctor may recommend complementary tests such as stool antigen testing or urea breath tests to confirm current bacterial activity before prescribing treatment.

Many people with positive antibody tests have no current symptoms, as H. pylori can remain present without causing obvious problems (i.e. no active infection).

Clinical Decision Making

Your healthcare provider will interpret H. pylori antibody results alongside your symptoms, medical history, and other factors to determine the most appropriate next steps. This might include additional testing to confirm active infection, treatment if clinical evidence suggests current infection, or monitoring if symptoms are minimal.

The decision to treat H. pylori depends on various factors including symptom severity, ulcer history, family history of stomach cancer, and individual risk factors that make treatment more beneficial than continued observation.

The Takeaway

H. pylori IgG antibody testing provides valuable information about your exposure to this common bacterial infection that can cause stomach problems and digestive complications. Many people carry H. pylori without symptoms, whilst others experience ongoing discomfort that can be effectively treated once the infection is identified.

If your H. pylori antibodies are positive, this indicates bacterial exposure, past or present, that may explain persistent stomach symptoms or could potentially cause problems in the future. Understanding these results helps guide appropriate testing and treatment decisions to protect your digestive health and prevent complications.

A simple blood test can reveal whether you've been exposed to H. pylori and help determine if this common bacterial infection might be affecting your stomach health. Working with your healthcare team to interpret these results ensures that any active infection receives appropriate evaluation and treatment when beneficial.

The Takeaway

H. pylori IgG antibody testing provides valuable information about your exposure to this common bacterial infection that can cause stomach problems and digestive complications. Many people carry H. pylori without symptoms, whilst others experience ongoing discomfort that can be effectively treated once the infection is identified.

If your H. pylori antibodies are positive, this indicates bacterial exposure, past or present, that may explain persistent stomach symptoms or could potentially cause problems in the future. Understanding these results helps guide appropriate testing and treatment decisions to protect your digestive health and prevent complications.

A simple blood test can reveal whether you've been exposed to H. pylori and help determine if this common bacterial infection might be affecting your stomach health. Working with your healthcare team to interpret these results ensures that any active infection receives appropriate evaluation and treatment when beneficial.

The Takeaway

H. pylori IgG antibody testing provides valuable information about your exposure to this common bacterial infection that can cause stomach problems and digestive complications. Many people carry H. pylori without symptoms, whilst others experience ongoing discomfort that can be effectively treated once the infection is identified.

If your H. pylori antibodies are positive, this indicates bacterial exposure, past or present, that may explain persistent stomach symptoms or could potentially cause problems in the future. Understanding these results helps guide appropriate testing and treatment decisions to protect your digestive health and prevent complications.

A simple blood test can reveal whether you've been exposed to H. pylori and help determine if this common bacterial infection might be affecting your stomach health. Working with your healthcare team to interpret these results ensures that any active infection receives appropriate evaluation and treatment when beneficial.

References

  1. National Institute for Health and Care Excellence. (2020). Helicobacter pylori infection: diagnosis and management. NICE Clinical Guideline.

  2. British Society of Gastroenterology. (2021). Guidelines for H. pylori testing and treatment. BSG Practice Standards.

  3. Royal College of General Practitioners. (2020). Management of dyspepsia and H. pylori infection. RCGP Clinical Guidelines.

References

  1. National Institute for Health and Care Excellence. (2020). Helicobacter pylori infection: diagnosis and management. NICE Clinical Guideline.

  2. British Society of Gastroenterology. (2021). Guidelines for H. pylori testing and treatment. BSG Practice Standards.

  3. Royal College of General Practitioners. (2020). Management of dyspepsia and H. pylori infection. RCGP Clinical Guidelines.

References

  1. National Institute for Health and Care Excellence. (2020). Helicobacter pylori infection: diagnosis and management. NICE Clinical Guideline.

  2. British Society of Gastroenterology. (2021). Guidelines for H. pylori testing and treatment. BSG Practice Standards.

  3. Royal College of General Practitioners. (2020). Management of dyspepsia and H. pylori infection. RCGP Clinical Guidelines.

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Subscribe to our newsletter

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Subscribe to our newsletter

© 2025 Emerald Labs Ltd

Subscribe to our newsletter

© 2025 Emerald Labs Ltd