Type

Type

Blood

Blood

Part of

Nutritional health

Part of

Nutritional health

Blood biomarker

Albumin

Albumin

Albumin is a protein made by the liver that helps maintain fluid balance.

Albumin is a protein made by the liver that helps maintain fluid balance.

Albumin

Normal range

Normal range

35-50 g/L

35-50 g/L

Normal range

35-50 g/L

35-50 g/L

Normal range

Albumin

Albumin

Albumin is a protein made by the liver that helps maintain fluid balance.

Albumin

Normal range

35-50 g/L

Normal range

35-50 g/L

35-50 g/L

Normal range

Albumin

Albumin

Albumin is a protein made by the liver that helps maintain fluid balance.

Albumin

Normal range

35-50 g/L

Normal range

35-50 g/L

35-50 g/L

Normal range

Albumin

Dr. Thiviya Sivakanthan

MBBS

Your Blood's Essential Transport Protein

Your Blood's Essential Transport Protein

Every day, your liver produces albumin, the most abundant protein in your bloodstream that works like your body's multitasking champion—carrying nutrients and medications throughout your circulation, maintaining proper fluid balance, and supporting healing processes. When albumin levels drop, it can indicate liver problems, nutritional deficiencies, or chronic illnesses that are interfering with your body's ability to produce or maintain this essential protein.

Albumin serves as your blood's primary workhorse protein, performing critical functions that keep your circulatory system operating smoothly and your tissues properly nourished. Think of it as your internal transport and maintenance system—when albumin levels are normal, your blood carries nutrients efficiently and maintains proper fluid balance, but when they drop, it signals that your body's protein production or retention systems need attention.

Every day, your liver produces albumin, the most abundant protein in your bloodstream that works like your body's multitasking champion—carrying nutrients and medications throughout your circulation, maintaining proper fluid balance, and supporting healing processes. When albumin levels drop, it can indicate liver problems, nutritional deficiencies, or chronic illnesses that are interfering with your body's ability to produce or maintain this essential protein.

Albumin serves as your blood's primary workhorse protein, performing critical functions that keep your circulatory system operating smoothly and your tissues properly nourished. Think of it as your internal transport and maintenance system—when albumin levels are normal, your blood carries nutrients efficiently and maintains proper fluid balance, but when they drop, it signals that your body's protein production or retention systems need attention.

When Albumin Levels Drop

When Albumin Levels Drop

When Albumin Levels Drop

Discover how low albumin can indicate liver problems, poor nutrition, or chronic diseases that affect protein production and retention.

Read more

What Affects Your Albumin Production

What Affects Your Albumin Production

What Affects Your Albumin Production

From liver function to dietary protein, learn what influences your body's ability to make and maintain this vital protein.

Read more

The Albumin Transport System

The Albumin Transport System

The Albumin Transport System

Understanding how this protein carries nutrients, maintains fluid balance, and supports your body's essential functions.

Read more

Understanding Your Results

Understanding Your Results

Understanding Your Results

Decode your numbers and know what your albumin levels reveal about your liver health, nutrition, and overall wellbeing.

Read more

When Albumin Levels Drop

Low albumin levels, called hypoalbuminemia, indicate that your body either isn't producing enough of this essential protein or is losing it faster than it can be replaced. You might notice swelling in your legs, ankles, or abdomen as fluid shifts from your bloodstream into your tissues without adequate albumin to maintain proper fluid balance.

Liver-related albumin deficiency occurs when your liver cannot produce adequate amounts due to liver disease, damage, or dysfunction. Since your liver is the sole source of albumin production, any condition that significantly impairs liver function can reduce albumin levels and affect multiple body systems that depend on this protein.

Nutritional causes of low albumin include inadequate protein intake, malabsorption problems, or chronic illnesses that increase protein needs beyond what your diet provides. Your body requires adequate amino acids to produce albumin, and deficiencies can develop when intake is insufficient or absorption is impaired.

Protein loss through your kidneys, intestines, or wounds can also cause albumin levels to drop even when production remains normal. Kidney disease, inflammatory bowel conditions, or severe burns can all cause excessive albumin loss that overwhelms your liver's production capacity.

When Albumin Levels Drop

Low albumin levels, called hypoalbuminemia, indicate that your body either isn't producing enough of this essential protein or is losing it faster than it can be replaced. You might notice swelling in your legs, ankles, or abdomen as fluid shifts from your bloodstream into your tissues without adequate albumin to maintain proper fluid balance.

Liver-related albumin deficiency occurs when your liver cannot produce adequate amounts due to liver disease, damage, or dysfunction. Since your liver is the sole source of albumin production, any condition that significantly impairs liver function can reduce albumin levels and affect multiple body systems that depend on this protein.

Nutritional causes of low albumin include inadequate protein intake, malabsorption problems, or chronic illnesses that increase protein needs beyond what your diet provides. Your body requires adequate amino acids to produce albumin, and deficiencies can develop when intake is insufficient or absorption is impaired.

Protein loss through your kidneys, intestines, or wounds can also cause albumin levels to drop even when production remains normal. Kidney disease, inflammatory bowel conditions, or severe burns can all cause excessive albumin loss that overwhelms your liver's production capacity.

When Albumin Levels Drop

Low albumin levels, called hypoalbuminemia, indicate that your body either isn't producing enough of this essential protein or is losing it faster than it can be replaced. You might notice swelling in your legs, ankles, or abdomen as fluid shifts from your bloodstream into your tissues without adequate albumin to maintain proper fluid balance.

Liver-related albumin deficiency occurs when your liver cannot produce adequate amounts due to liver disease, damage, or dysfunction. Since your liver is the sole source of albumin production, any condition that significantly impairs liver function can reduce albumin levels and affect multiple body systems that depend on this protein.

Nutritional causes of low albumin include inadequate protein intake, malabsorption problems, or chronic illnesses that increase protein needs beyond what your diet provides. Your body requires adequate amino acids to produce albumin, and deficiencies can develop when intake is insufficient or absorption is impaired.

Protein loss through your kidneys, intestines, or wounds can also cause albumin levels to drop even when production remains normal. Kidney disease, inflammatory bowel conditions, or severe burns can all cause excessive albumin loss that overwhelms your liver's production capacity.

What Affects Your Albumin Production

Your liver's health directly determines your albumin production capacity, as this organ is solely responsible for manufacturing all the albumin in your bloodstream. Liver diseases including hepatitis, cirrhosis, or fatty liver disease can significantly reduce albumin production, whilst liver damage from alcohol, medications, or toxins can impair this essential function.

Dietary protein intake provides the building blocks your liver needs to produce albumin. Inadequate protein consumption, particularly over extended periods, can limit your liver's ability to maintain normal albumin production even when liver function is otherwise healthy.

Chronic inflammatory conditions can suppress albumin production as your body redirects resources toward immune responses and healing processes. Conditions like rheumatoid arthritis, inflammatory bowel disease, or chronic infections can all reduce albumin levels through these inflammatory pathways.

Age affects albumin production, with levels typically declining gradually in older adults due to reduced liver function, decreased protein intake, or the cumulative effects of chronic health conditions that become more common with aging.

What Affects Your Albumin Production

Your liver's health directly determines your albumin production capacity, as this organ is solely responsible for manufacturing all the albumin in your bloodstream. Liver diseases including hepatitis, cirrhosis, or fatty liver disease can significantly reduce albumin production, whilst liver damage from alcohol, medications, or toxins can impair this essential function.

Dietary protein intake provides the building blocks your liver needs to produce albumin. Inadequate protein consumption, particularly over extended periods, can limit your liver's ability to maintain normal albumin production even when liver function is otherwise healthy.

Chronic inflammatory conditions can suppress albumin production as your body redirects resources toward immune responses and healing processes. Conditions like rheumatoid arthritis, inflammatory bowel disease, or chronic infections can all reduce albumin levels through these inflammatory pathways.

Age affects albumin production, with levels typically declining gradually in older adults due to reduced liver function, decreased protein intake, or the cumulative effects of chronic health conditions that become more common with aging.

What Affects Your Albumin Production

Your liver's health directly determines your albumin production capacity, as this organ is solely responsible for manufacturing all the albumin in your bloodstream. Liver diseases including hepatitis, cirrhosis, or fatty liver disease can significantly reduce albumin production, whilst liver damage from alcohol, medications, or toxins can impair this essential function.

Dietary protein intake provides the building blocks your liver needs to produce albumin. Inadequate protein consumption, particularly over extended periods, can limit your liver's ability to maintain normal albumin production even when liver function is otherwise healthy.

Chronic inflammatory conditions can suppress albumin production as your body redirects resources toward immune responses and healing processes. Conditions like rheumatoid arthritis, inflammatory bowel disease, or chronic infections can all reduce albumin levels through these inflammatory pathways.

Age affects albumin production, with levels typically declining gradually in older adults due to reduced liver function, decreased protein intake, or the cumulative effects of chronic health conditions that become more common with aging.

The Albumin Transport System

Albumin works like your blood's cargo ship, carrying various substances throughout your circulation including hormones, vitamins, medications, and fatty acids. This transport function ensures that important nutrients and therapeutic compounds reach their target tissues effectively and efficiently.

The protein also serves as your blood's fluid manager, that keeps appropriate amounts of fluid within your blood vessels rather than leaking into surrounding tissues. When albumin levels drop, this fluid management system fails, leading to swelling and oedema formation.

Albumin acts as a buffer system that helps maintain proper pH balance in your blood, whilst also serving as a protein reserve that your body can use during times of increased need such as illness, injury, or inadequate nutrition. This reserve function makes albumin an important indicator of your body's protein status.

The protein's binding capacity also helps transport medications throughout your body and can affect how drugs work, making albumin levels important for understanding medication effectiveness and dosing requirements in people with low levels.

The Albumin Transport System

Albumin works like your blood's cargo ship, carrying various substances throughout your circulation including hormones, vitamins, medications, and fatty acids. This transport function ensures that important nutrients and therapeutic compounds reach their target tissues effectively and efficiently.

The protein also serves as your blood's fluid manager, that keeps appropriate amounts of fluid within your blood vessels rather than leaking into surrounding tissues. When albumin levels drop, this fluid management system fails, leading to swelling and oedema formation.

Albumin acts as a buffer system that helps maintain proper pH balance in your blood, whilst also serving as a protein reserve that your body can use during times of increased need such as illness, injury, or inadequate nutrition. This reserve function makes albumin an important indicator of your body's protein status.

The protein's binding capacity also helps transport medications throughout your body and can affect how drugs work, making albumin levels important for understanding medication effectiveness and dosing requirements in people with low levels.

The Albumin Transport System

Albumin works like your blood's cargo ship, carrying various substances throughout your circulation including hormones, vitamins, medications, and fatty acids. This transport function ensures that important nutrients and therapeutic compounds reach their target tissues effectively and efficiently.

The protein also serves as your blood's fluid manager, that keeps appropriate amounts of fluid within your blood vessels rather than leaking into surrounding tissues. When albumin levels drop, this fluid management system fails, leading to swelling and oedema formation.

Albumin acts as a buffer system that helps maintain proper pH balance in your blood, whilst also serving as a protein reserve that your body can use during times of increased need such as illness, injury, or inadequate nutrition. This reserve function makes albumin an important indicator of your body's protein status.

The protein's binding capacity also helps transport medications throughout your body and can affect how drugs work, making albumin levels important for understanding medication effectiveness and dosing requirements in people with low levels.

Understanding Your Results 

Albumin levels reflect your liver's protein production capacity and your body's overall protein status. Understanding these ranges helps assess whether your protein systems are functioning effectively:


Albumin Ranges: 

  • Normal levels: 35-52 g/L 

  • Mildly low: 30-34 g/L 

  • Moderately low: 25-29 g/L 

  • Significantly low: <25 g/L


These ranges represent normal protein production and retention - staying within these bounds suggests your liver is producing adequate albumin and your body is maintaining proper protein balance, whilst low levels indicate problems that need evaluation and intervention.

Understanding Low Levels

Mildly low albumin often indicates early liver dysfunction, nutritional inadequacy, or chronic inflammatory conditions that are beginning to affect protein production or retention. These levels typically prompt investigation for underlying causes and nutritional assessment.

Moderately to significantly low levels usually indicate more serious problems requiring prompt medical evaluation and intervention. Very low albumin can cause complications including fluid retention, increased infection risk, and poor wound healing that need active management.

Clinical Implications

Your doctor will interpret albumin results alongside your symptoms, other liver tests, nutritional assessment, and medical history to determine the underlying cause of any deficiency. This comprehensive approach helps distinguish between liver problems, nutritional issues, protein loss, or chronic inflammatory conditions.

Low albumin levels can affect medication dosing and effectiveness, wound healing capacity, and immune function, making correction of underlying causes important for optimal health outcomes and treatment effectiveness.

Understanding Your Results 

Albumin levels reflect your liver's protein production capacity and your body's overall protein status. Understanding these ranges helps assess whether your protein systems are functioning effectively:


Albumin Ranges: 

  • Normal levels: 35-52 g/L 

  • Mildly low: 30-34 g/L 

  • Moderately low: 25-29 g/L 

  • Significantly low: <25 g/L


These ranges represent normal protein production and retention - staying within these bounds suggests your liver is producing adequate albumin and your body is maintaining proper protein balance, whilst low levels indicate problems that need evaluation and intervention.

Understanding Low Levels

Mildly low albumin often indicates early liver dysfunction, nutritional inadequacy, or chronic inflammatory conditions that are beginning to affect protein production or retention. These levels typically prompt investigation for underlying causes and nutritional assessment.

Moderately to significantly low levels usually indicate more serious problems requiring prompt medical evaluation and intervention. Very low albumin can cause complications including fluid retention, increased infection risk, and poor wound healing that need active management.

Clinical Implications

Your doctor will interpret albumin results alongside your symptoms, other liver tests, nutritional assessment, and medical history to determine the underlying cause of any deficiency. This comprehensive approach helps distinguish between liver problems, nutritional issues, protein loss, or chronic inflammatory conditions.

Low albumin levels can affect medication dosing and effectiveness, wound healing capacity, and immune function, making correction of underlying causes important for optimal health outcomes and treatment effectiveness.

Understanding Your Results 

Albumin levels reflect your liver's protein production capacity and your body's overall protein status. Understanding these ranges helps assess whether your protein systems are functioning effectively:


Albumin Ranges: 

  • Normal levels: 35-52 g/L 

  • Mildly low: 30-34 g/L 

  • Moderately low: 25-29 g/L 

  • Significantly low: <25 g/L


These ranges represent normal protein production and retention - staying within these bounds suggests your liver is producing adequate albumin and your body is maintaining proper protein balance, whilst low levels indicate problems that need evaluation and intervention.

Understanding Low Levels

Mildly low albumin often indicates early liver dysfunction, nutritional inadequacy, or chronic inflammatory conditions that are beginning to affect protein production or retention. These levels typically prompt investigation for underlying causes and nutritional assessment.

Moderately to significantly low levels usually indicate more serious problems requiring prompt medical evaluation and intervention. Very low albumin can cause complications including fluid retention, increased infection risk, and poor wound healing that need active management.

Clinical Implications

Your doctor will interpret albumin results alongside your symptoms, other liver tests, nutritional assessment, and medical history to determine the underlying cause of any deficiency. This comprehensive approach helps distinguish between liver problems, nutritional issues, protein loss, or chronic inflammatory conditions.

Low albumin levels can affect medication dosing and effectiveness, wound healing capacity, and immune function, making correction of underlying causes important for optimal health outcomes and treatment effectiveness.

The Takeaway

Albumin levels provide important information about your liver's protein production capacity, nutritional status, and overall health. Low levels can indicate various problems ranging from liver disease to poor nutrition, but most causes are treatable when identified early and addressed appropriately.

If your albumin levels are low, this indicates that your body's protein production or retention systems need evaluation and support. These measurements reflect your liver's ability to produce essential proteins and your body's capacity to maintain the protein balance necessary for optimal function.

A simple blood test can reveal whether your albumin levels are supporting proper fluid balance and nutrient transport or indicating problems that need medical attention. Understanding your results helps you work with your healthcare team to identify and address any conditions affecting your liver function, nutrition, or protein balance.

The Takeaway

Albumin levels provide important information about your liver's protein production capacity, nutritional status, and overall health. Low levels can indicate various problems ranging from liver disease to poor nutrition, but most causes are treatable when identified early and addressed appropriately.

If your albumin levels are low, this indicates that your body's protein production or retention systems need evaluation and support. These measurements reflect your liver's ability to produce essential proteins and your body's capacity to maintain the protein balance necessary for optimal function.

A simple blood test can reveal whether your albumin levels are supporting proper fluid balance and nutrient transport or indicating problems that need medical attention. Understanding your results helps you work with your healthcare team to identify and address any conditions affecting your liver function, nutrition, or protein balance.

The Takeaway

Albumin levels provide important information about your liver's protein production capacity, nutritional status, and overall health. Low levels can indicate various problems ranging from liver disease to poor nutrition, but most causes are treatable when identified early and addressed appropriately.

If your albumin levels are low, this indicates that your body's protein production or retention systems need evaluation and support. These measurements reflect your liver's ability to produce essential proteins and your body's capacity to maintain the protein balance necessary for optimal function.

A simple blood test can reveal whether your albumin levels are supporting proper fluid balance and nutrient transport or indicating problems that need medical attention. Understanding your results helps you work with your healthcare team to identify and address any conditions affecting your liver function, nutrition, or protein balance.

References

  1. National Institute for Health and Care Excellence. (2021). Liver function assessment: clinical interpretation. NICE Clinical Guideline.

  2. British Society of Gastroenterology. (2020). Hypoalbuminemia: causes and management. BSG Practice Guidelines.

  3. Royal College of Physicians. (2021). Protein-energy malnutrition: recognition and treatment. RCP Clinical Standards.

References

  1. National Institute for Health and Care Excellence. (2021). Liver function assessment: clinical interpretation. NICE Clinical Guideline.

  2. British Society of Gastroenterology. (2020). Hypoalbuminemia: causes and management. BSG Practice Guidelines.

  3. Royal College of Physicians. (2021). Protein-energy malnutrition: recognition and treatment. RCP Clinical Standards.

References

  1. National Institute for Health and Care Excellence. (2021). Liver function assessment: clinical interpretation. NICE Clinical Guideline.

  2. British Society of Gastroenterology. (2020). Hypoalbuminemia: causes and management. BSG Practice Guidelines.

  3. Royal College of Physicians. (2021). Protein-energy malnutrition: recognition and treatment. RCP Clinical Standards.

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Subscribe to our newsletter

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Subscribe to our newsletter

© 2025 Emerald Labs Ltd