Longevity & Prevention

·

5 min

Dr Shad Asinger

MBBS GPST

Longevity: The Essential Role of Magnesium in Your Health

Longevity: The Essential Role of Magnesium in Your Health

Longevity: The Essential Role of Magnesium in Your Health

Struggling with poor sleep, low energy, or stress overload? You might be missing one vital mineral: magnesium. Often overlooked, magnesium has a role in everything from calming your nervous system to powering your muscles and brain.

Feeling constantly tired despite getting enough sleep? Experiencing muscle cramps, anxiety, or trouble winding down at night? These seemingly unrelated symptoms might all point to one crucial missing piece in your wellness puzzle: adequate magnesium. Discover how this often-overlooked mineral affects everything from your sleep to your mood, and learn whether you're getting enough to support your body's complex needs.

Understanding how magnesium works in your body—and what you can do about it—can be transformative for your overall wellbeing and quality of life.

Why Magnesium Deserves Your Attention

Magnesium doesn’t get the spotlight that vitamin D or omega-3s do, but it absolutely should. This essential mineral is like a master key, unlocking over 600 different processes in your body. Think of it as your internal maintenance crew, working 24/7 to keep everything running smoothly—from your heartbeat to your brain function to your ability to relax and sleep. It also plays a critical role in brain function, with low levels being linked to an increased risk of depression.

Magnesium helps your cells produce energy, supports your muscles and nerves, keeps your blood sugar stable by improving insulin sensitivity, maintains healthy blood pressure, and even helps your body make proteins. Without enough magnesium, it’s like trying to run a complex machine with missing parts—things start to feel off, even if you can’t pinpoint exactly why. Additionally, magnesium helps move blood sugar into your muscles and dispose of lactate, aiding exercise performance. Studies show that magnesium supplements may improve blood sugar levels and insulin sensitivity in people at risk for type 2 diabetes.

But here’s where it gets really interesting for your daily life: magnesium directly influences your sleep quality by helping your body produce melatonin (your natural sleep hormone) and activating your “rest and digest” nervous system. It also helps control cortisol—your main stress hormone—and supports the production of GABA, a brain chemical that helps you feel calm and centred.

If you’ve ever wondered why you crave chocolate when you’re stressed, here’s a clue: dark chocolate is actually rich in magnesium. Your body might be trying to tell you something.

The Testing Challenge: Why Standard Blood Tests Miss the Mark

Here’s something most people don’t know: the standard magnesium test your doctor orders—called serum magnesium—only shows a tiny slice of the picture. It measures the magnesium floating around in your blood, which is just 1% of what’s actually in your body. The other 99% is stored in your bones, muscles, and organs where it’s actually doing its job. In fact, most magnesium is found in bones and soft tissues, not in the blood.

Your body is incredibly smart about keeping blood magnesium levels stable. When your tissue stores start running low, your body will pull magnesium from your bones and muscles to keep your blood levels looking “normal.” It’s like borrowing from your savings account to keep your checking account balance steady—everything looks fine on the surface, but you’re actually running low on reserves.

This means you can feel tired, crampy, anxious, or have trouble sleeping while your blood test comes back “normal.” It’s frustrating, but it explains why so many people struggle with these symptoms without getting answers. As magnesium deficiency worsens, symptoms can include numbness, tingling, muscle contractions and cramps, seizures, personality changes, abnormal heart rhythms, and coronary spasms.

The reality is that at least 20% of people are clinically low in magnesium, while up to 80% may not be getting enough to feel their best—even though their blood tests don’t flag any problems. Low magnesium intake is also associated with increased levels of inflammation, which plays a crucial role in aging and chronic disease.

Are You Getting Enough? Signs Your Body Might Be Asking for More Magnesium

Magnesium deficiency doesn’t usually announce itself with dramatic symptoms. Instead, it tends to show up as those nagging issues that you might chalk up to stress, getting older, or just being busy. Here’s what to watch for:

Your muscles are trying to tell you something. Muscle cramps, especially in your calves or feet at night, are classic signs. You might also notice muscle twitching, persistent tension in your neck and shoulders, or that your jaw feels tight. Some people describe their muscles as feeling “reactive” or easily triggered.

Sleep becomes elusive. This is a big one. You might find yourself tired but unable to wind down, or you fall asleep fine but wake up multiple times during the night. Many people describe feeling “tired but wired”—like their body is exhausted but their mind won’t switch off.

Your mood feels more fragile. Anxiety might feel more intense than usual, or you might find yourself irritated by things that normally wouldn’t bother you. Some people notice they feel emotionally raw or like their usual coping strategies aren’t working as well.

Your brain feels foggy. Difficulty concentrating, memory issues, or that feeling like you’re thinking through molasses can all be connected to magnesium. You might find yourself reading the same sentence multiple times or forgetting what you walked into a room to get.

Your digestion gets sluggish. Constipation is common when magnesium is low, since this mineral helps your intestinal muscles function properly. You might also notice more sugar cravings, especially for chocolate.

Your heart feels skippy. Heart palpitations or that feeling like your heart is racing for no reason can sometimes be related to magnesium levels.

Everything feels more intense. You might notice you’re more sensitive to noise, light, caffeine, or stress than you used to be.

For those going through hormonal changes—whether that’s monthly cycles, pregnancy, perimenopause, or other transitions—adequate magnesium becomes even more important for maintaining emotional balance and physical comfort.

Addressing magnesium deficiency can help reduce symptoms such as muscle cramps, sleep disturbances, and mood changes.

How Much Magnesium Do You Really Need?

Why Modern Life is Working Against Your Magnesium Levels

Understanding why magnesium deficiency has become so common requires looking at what’s changed in our world over the past several decades. It’s not just one thing—it’s a perfect storm.

Our food isn’t what it used to be.* Modern farming practices have gradually depleted magnesium from the soil. Studies show that the magnesium content in vegetables has dropped by about 25% since the 1940s. So even when you’re eating spinach and almonds (both high-magnesium foods), you’re getting less than your grandparents did from the same foods. Dietary surveys also show that many people in the United States consume less magnesium than recommended amounts.*

Processing strips away the good stuff.* When whole grains become white flour, or brown rice becomes white rice, up to 80% of the magnesium gets removed. Since processed foods make up a huge portion of the typical Western diet, many people are eating very little naturally occurring magnesium.*

Stress is magnesium’s biggest enemy.* When you’re stressed, your body burns through magnesium faster to produce stress hormones and keep your nervous system functioning. But here’s the cruel irony: magnesium is exactly what your body needs to handle stress well. So stress depletes magnesium, which makes you less able to handle stress, which depletes more magnesium. It becomes a vicious cycle.*

Your daily habits might be working against you.* Coffee and alcohol both increase how much magnesium your kidneys excrete. A glass of wine or a cup of coffee isn’t a problem, but regular consumption can slowly chip away at your levels over time.*

Common medications can interfere.* Certain medications, such as heartburn medications (proton pump inhibitors), water pills (diuretics), birth control pills, and antibiotics, can all either block magnesium absorption or increase how much you lose. Even over-the-counter medications can have subtle effects. Certain medications can reduce magnesium absorption from the gut, increasing the risk of deficiency.*

Gut health issues create absorption problems.* If you’re dealing with digestive issues—whether that’s irritable bowel syndrome, SIBO (small intestinal bacterial overgrowth), or chronic inflammation—your body might not be absorbing magnesium efficiently from food. Conditions like Crohn's disease can significantly impair intestinal absorption of magnesium, making it harder to maintain proper levels. Impaired intestinal absorption is a key reason why some people develop magnesium deficiency, especially in the context of gastrointestinal disorders.*

Getting Magnesium from Food: The Foundation

Before we talk supplements, let's start with food. While it's harder to get enough magnesium from food alone than it used to be, building a foundation of magnesium-rich foods is still the best place to start. Bananas are a source of magnesium, with a medium banana providing about 32mg (roughly 11% of your daily needs), making them another easy and accessible option to include in your diet.

Green leafy vegetables are magnesium powerhouses. A 100g serving of cooked spinach provides about 79mg (28% of daily needs), while Swiss chard offers 81mg (28%), and kale provides substantial amounts as well. Here's a fun fact: the green color in plants comes from chlorophyll, and at the center of every chlorophyll molecule is a magnesium atom. So when you eat greens, you're getting magnesium in one of nature's most bioavailable forms.

Nuts and seeds pack a punch. Pumpkin seeds (pepitas) are the champions here—just 28g (about 2 tablespoons) provides approximately 262mg, which is nearly 90% of your daily needs. A 28g serving of almonds gives you 76mg (27%), cashews provide 83mg (29%), sunflower seeds offer 91mg (32%), and Brazil nuts deliver 107mg (38% of daily needs). Keep them visible on your counter so you remember to snack on them.

Whole grains still matter. A 100g serving of cooked quinoa provides about 64mg (22% of daily needs), while brown rice offers 43mg (15%). When grains are left in their natural state, they retain their magnesium content. Ancient grains like amaranth and teff can be particularly rich sources.

Don't forget legumes. A 100g serving of cooked black beans provides about 70mg (25% of daily needs), chickpeas offer 48mg (17%), and lentils provide 36mg (13%), along with fiber and protein. They're budget-friendly and versatile too.

Dark chocolate is better. Choose chocolate that's 70% cacao or higher—a 28g piece provides about 64mg (22% of daily needs), along with compounds that support heart health and mood. This might explain those chocolate cravings during stressful times—your body knows what it needs.

Avocados are the perfect package. A medium avocado provides about 29mg (10% of daily needs) along with healthy fats that help your body absorb fat-soluble vitamins and other nutrients.

Many foods, including nuts, seeds, whole grains, and green leafy vegetables, are excellent food sources of magnesium. Including a variety of food sources in your diet is important for meeting your magnesium needs.

However, even with the best dietary intentions, many people find it challenging to get optimal amounts from food alone. The combination of depleted soil, food processing, and our increased needs due to modern stressors means that supplements often become a helpful addition.

Navigating Magnesium Supplements: Which Form is Right for You?

Walk down the supplement aisle, and you’ll see magnesium citrate, magnesium glycinate, magnesium oxide, and a dozen other options. For those who cannot meet their magnesium needs through food alone, magnesium supplementation and dietary supplements can help improve magnesium status and support health. Small studies have found that magnesium in the aspartate, citrate, lactate, and chloride forms is absorbed more completely and is more bioavailable than magnesium oxide and magnesium sulfate. Forms of magnesium that dissolve well in liquid are more completely absorbed in the gut than less soluble forms.

Magnesium Glycinate: The Gentle, All-Purpose Choice

This is often the best place to start if you're new to magnesium supplements. Magnesium glycinate combines magnesium with glycine, an amino acid that has calming properties of its own. Think of it as magnesium with a built-in relaxation bonus.

Why it works well: It's easy on your stomach (no digestive upset), well-absorbed by your body, and the glycine component enhances the calming effects. Many people notice improvements in sleep quality, anxiety levels, and muscle tension.

Best for: Sleep issues, anxiety, muscle tension, general stress, or if you just want reliable daily magnesium support without digestive side effects.

How to use it: Take 200-400mg about 30-60 minutes before bedtime. The timing allows it to start working as your body naturally begins winding down for sleep.

Magnesium Citrate: The Digestive Helper

Magnesium citrate combines magnesium with citric acid, creating a form that's well-absorbed and particularly good for digestive health. It has a gentle laxative effect, which can be either a benefit or a drawback depending on what you need.

Why it works well: It draws water into your intestines, which softens stool and can help with constipation. It's also well-absorbed and readily available.

Best for: Occasional constipation, digestive sluggishness, or when you're traveling and want to stay regular. It's also a good choice if you want magnesium support with the bonus of digestive help.

How to use it: Start with a smaller dose (150-200mg) and adjust based on your body's response. Too much too fast can lead to loose stools, which isn't dangerous but isn't comfortable either.

Magnesium L-Threonate: The Brain-Focused Option

This is the newer kid on the block, specifically designed to cross the blood-brain barrier more effectively than other forms. It was developed with cognitive health in mind.

Why it's different: Most magnesium supplements don't easily get into brain tissue, but L-threonate was specifically designed to solve this problem. Early research suggests it may be particularly beneficial for memory, focus, and mental clarity.

Best for: Brain fog, concentration issues, memory concerns, or if you're particularly interested in cognitive support. It may also help with sleep and anxiety, especially when these issues feel more "mental" than physical.

How to use it: This one can be taken during the day or evening, depending on how it affects your energy levels. Some people find it slightly energising, while others find it calming.

Topical Magnesium: The External Approach

If you prefer not to take oral supplements, or want to target specific areas of muscle tension, topical magnesium can be surprisingly effective. This includes magnesium oil (which isn't actually oily), lotions, and good old-fashioned Epsom salt baths.

Why it works: Your skin can absorb magnesium directly into your bloodstream, bypassing your digestive system entirely. It's particularly good for targeting specific areas of muscle tension or cramping.

Best for: Localised muscle tension, if you have digestive issues that interfere with oral supplements, or if you just prefer a more relaxing, spa-like approach.

How to use it: Epsom salt baths before bed can be incredibly relaxing. For magnesium oil, start with a small amount on clean skin and see how your body responds—some people experience tingling initially, which usually subsides with regular use.

Magnesium Oxide: The Targeted Laxative

Magnesium oxide serves a different purpose entirely and shouldn't be confused with other magnesium supplements. While it's the cheapest and most widely available form, it's poorly absorbed by the body—which is actually intentional. Magnesium oxide is primarily used as a laxative for occasional constipation relief rather than for general magnesium supplementation.

If your goal is to increase your overall magnesium levels for health benefits like better sleep, muscle function, or stress management, magnesium oxide isn't the right choice. 

Getting Your Magnesium Routine Right

Start low and go slow.* Most people do well with 200-400mg daily, but it’s best to start with a lower dose and gradually increase. This gives your body time to adjust and helps you find your sweet spot without digestive upset. Some individuals, such as those with certain health conditions like preeclampsia or eclampsia, may require extra magnesium under medical supervision.*

Timing can make a difference.* For sleep support, take magnesium 30-60 minutes before bed. For all-day stress support, you might split your dose between morning and evening. If you’re using citrate for digestive support, an empty stomach might work better, but start with food if you’re sensitive.*

Take it with food initially.* This can help prevent any stomach upset while your body gets used to the supplement. Once you’re comfortable, you can experiment with timing.*

Be patient.* While some people notice effects within a few days, it can take several weeks to build up your body’s magnesium stores and experience the full benefits. Give it at least a month before deciding if it’s working for you.*

Pay attention to your body’s signals.* If you experience digestive upset, try a different form or lower dose. If you’re not noticing any benefits after 4-6 weeks, you might need to adjust your dose or try a different form.*

Supporting Your Magnesium Absorption

Magnesium doesn’t work alone—it’s part of a team of nutrients that support each other. Understanding these relationships can help you get the most from your efforts.

Vitamin D needs magnesium to work properly. If you’re taking vitamin D supplements (and many people are), you need adequate magnesium to activate it in your body. On the flip side, vitamin D helps your body absorb magnesium better. They’re partners.

B vitamins, especially B6, enhance magnesium’s benefits. This is particularly true for mood and energy support. If you’re dealing with stress or hormonal changes, a B-complex vitamin might enhance magnesium’s effects.

Balance calcium and magnesium thoughtfully. Both are important for bone health, but too much calcium without enough magnesium can cause problems. If you’re taking calcium supplements, make sure you’re getting adequate magnesium too. Severe magnesium deficiency can disrupt mineral homeostasis, leading to low serum calcium and affecting potassium levels, so maintaining adequate magnesium is essential for overall mineral balance.

Lifestyle factors matter. Stress management practices like meditation, yoga, or even regular walks can help your body utilise magnesium more effectively. Regular, moderate exercise also improves absorption and helps your body handle stress better.

Taking Your Next Step

If you decide to try supplementation, magnesium glycinate is often a good starting point—it's gentle, well-absorbed, and effective for the most common concerns people have. Start with 200-300mg about an hour before bedtime and give it several weeks to work.

Remember, optimal health is rarely about any single intervention. It's about creating conditions that allow your body to function at its best. Magnesium represents one of those fundamental building blocks—simple in concept, yet potentially profound in its impact on your daily life.

References

  1. Touyz RM, de Baaij JHF, Hoenderop JGJ. Magnesium Disorders. The New England Journal of Medicine. 2024;390(21):1998-2009.

  2. de Baaij JH, Hoenderop JG, Bindels RJ. Magnesium in Man: Implications for Health and Disease. Physiological Reviews. 2015;95(1):1-46.

  3. Fiorentini D, Cappadone C, Farruggia G, Prata C. Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency. Nutrients. 2021;13(4):1136.

  4. Pelczyńska M, Moszak M, Bogdański P. The Role of Magnesium in the Pathogenesis of Metabolic Disorders. Nutrients. 2022;14(9):1714.

  5. Barbagallo M, Veronese N, Dominguez LJ. Magnesium in Aging, Health and Diseases. Nutrients. 2021;13(2):463.

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